PRISM: Threat Level Red is the commercial version that sets the world and environments that inspire the Army National Guard's game PRISM: Black Shield. The commercial game will feature a more detailed story line along with a unique campaign structure. The game will also feature distinct missions, unique events, unique weapons, and a few more surprises.

PRISM: Threat Level Red will take place in the near future, with the player becoming the newest member of a secretive homeland defense unit known as PRISM. The core PRISM experience focuses on the unconventional application of new and emerging weapons and surveillance technologies in the war against terrorism. PRISM is an acronym for the Preemptive Reconnaissance and Identification Security Mainframe, a new computer system that the government is using to wirelessly hack into video surveillance equipment across America. When terrorist activities are suspected or potential targets are identified, players are called into action. This system will be the backbone of the game that drives both the story and the player.