This sounds, and looks, pretty awesome - a newly announced title at E3 from Konami called NeverDead, for Xbox 360 and PlayStation 3:

NEVERDEAD begins with the world under threat from a demonic plague. Centuries have passed since the world succumbed to an unforeseen shadow of evil, and a hero was made an immortal by demons. These demons have risen once again in the present day and are wreaked unrelenting mayhem, represented by destructible environments within the game. Cast as this immortal hero, the player can use regenerative powers to re-assemble his body to evade death – for he is Never Dead...

NEVERDEAD is a third-person action title set in a fantasy and horror-influenced universe of the near-future where supernatural battles between humans and extraordinary creatures span a vast city landscape. Players wield a unique butterfly design-inspired sword and an arsenal of guns, which are used to decimate waves of unholy enemies, and can rebuild their battle-weary body by collecting and repairing any lost limbs, and reattaching them.

The screenshots highlight the epic environments and foes you'll be battling and the trailer brings it all to life pretty vividly (despite some slightly OTT voice acting) - download in high definition for the full lush experience (404mb), or stream below.